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Database
National Autism Database
Established in January 2015, the National Autism Database embodies a unique multidisciplinary collaboration, with data contributed and shared by clinicians and scientists across pediatrics, neurology, psychiatry, genetics, neuroscience, developmental psychology, molecular biology, and biomedical engineering. Since its inception, we have continuously populated the resource with birth, clinical, and demographic records; parent questionnaires; behavioral test scores (including cognitive and ADOS assessments); EEG recordings; eye-tracking recordings; whole-exome DNA sequencing; prenatal ultrasound examinations; and MRI scans. The breadth of this dataset enables cross-domain analyses—for example, testing whether autistic children with specific genetic abnormalities also exhibit EEG abnormalities such as epileptiform activity—thereby accelerating discovery and advancing precision care.

Cohort Characteristics
The regional database includes records from 5,200+ autistic children and their families and continues to grow by roughly 15 new families each month. Over half were diagnosed before age 3 and more than 90% before age 6. The male-to-female ratio (~4:1) aligns with global estimates. About 25% of participating families are Bedouin—a historically underserved community in Israel—with high consanguinity rates (>60% first-cousin unions). This distinctive demographic profile enables analyses of how differences in genetic background and environmental exposure across communities shape autism risk.






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